The first meeting of the High Prairie and District Museum and Historical Society was held on July 26, 1961 in Pleasantview Lodge. They were given a $1000 grant from the Recreation Board.

The High Prairie Chamber of Commerce approves the joint Library and Museum project as a Canada Centennial initiative. Over two years, a number of fundraisers were held and grants were pursued.

The High Prairie & District Museum and Historical Society receives its Charter on June 24, 1967. The joint Library and Museum open shortly after as part of Centennial Days held July 11 and 13.

The Library and Museum building was expanded, but left the museum without a dedicated entrance.

The library moves to a new facility, and the museum takes over the entire facility. The space previously occupied by the museum is converted to dedicated storage space for artifacts and the archives and compact storage shelving is installed.

The High Prairie & District Museum recieves the Alberta Museum Associstion's 2023 Leadership Award for Engagement, in recognition of the museum's work to engage local settler and Indigenous communities through the development of their Truth and Reconciliation Gallery and the peyak mikwan – One Feather exhibit.

The museum's long-time curator retires, and the High Prairie & District Museum and Historical Society begins a conversation with the Town of High Prairie to take over operation of the museum. It is one of many museums across Alberta having similar discussions with their municipal government.

The Town of High Prairie assumes responsibility for the operation of the museum, nearly 59 years after it was first opened and a new chapter in the museum begins.